The science of longevity has been adopting a holistic and proactive view of health in order to prevent chronic disease, with integrative evaluation of health-related habits, including those associated with disease promotion and those related with general health and well-being1. Undertaking a review of current lifestyle habits, health status, and risk factors helps allows for an understanding of your overall health and well-being. These factors are the outcomes of dietary and non-dietary inputs into your biological health, how they interact with you gut microbiome and ultimately how these enter and play a role in your body to improve or detract from good health.
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Non-dietary lifestyle factor such as smoking and lack of exercise can significantly impact the large bowel (and potentially the microbiota). Smoking has a significant influence on gut microbiota composition, increasing Bacteroides-Prevotella in individuals with Crohn’s Disease (CD) and healthy individuals1. Smoking-induced changes in microbial populations could potentially contribute to increased risk of CD.
Stress, has an impact on colonic motor activity via the gut-brain axis which can alter gut microbiota profiles, including lower numbers of potentially beneficial Lactobacillus2. Stress may contribute to IBS, one of the most common functional bowel disorders, and the associated changes in microbial populations via the central nervous system (CNS). The gut-brain axis is bi-directional, involving both hormonal and neuronal pathways3, and so changes in the gut microbiota may influence brain activity, including mood4.
Exercise (or rather a lack of it) may be an important influence on any shifts in microbial populations that are associated with obesity. This is highlighted by a recent study that showed an increase in the diversity of gut microbial populations in professional athletes in response to exercise and the associated diet5. In humans and animal models with obesity, shifts in gut microbial populations occur, with increases in the Firmicutes and decreases in the Bacteroidetes, which could potentially contribute to adiposity through greater energy harvest6,7,8.
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A balanced diet is necessary for both good nutrition and health. Dietary lifestyle changes can primarily affect people by improving many parameters in one's health outcomes. A healthy diet has many advantages, such as enhancing mood, strengthening visceral organs' functions, and preventing various chronic diseases, including cancer, diabetes, and heart disease.
People consume various nutrients in their diet daily, but often fail to emphasize their effects on health outcomes. A healthy diet entails choosing a more nutritious diet over those with large amounts of trans fats, added salt, and sugar. Understanding how diet impacts your biological health - both microbiome and metabolic health is an important step toward potentially mitigating the onset of chronic diseases.